Carbapenemase

Nkọwa dị mkpirikpi:

A na-eji ngwa a maka nchọpụta qualitative nke NDM, KPC, OXA-48, IMP na VIM carbapenemases emepụtara na nje bacteria enwetara mgbe omenala na vitro gasịrị.

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HWTS-OT085E/F/G/H - Ngwa nchọpụta Carbapenemase (ọlaedo colloidal)

Epidemiology

Ọgwụ nje Carbapenem bụ ọgwụ nje β-lactam a na-ahụkarị nke nwere ụdị nje nje na-agbasa na yana ọrụ nje bacteria siri ike.^[1].N'ihi nkwụsi ike ya na β-lactamase na obere toxicity, ọ ghọọla otu n'ime ọgwụ nje antibacterial kachasị mkpa maka ọgwụgwọ ọrịa nje siri ike.Carbapenems kwụsiri ike na β-lactamases (ESBLs), chromosomes na cephalosporinases nke plasmid-mediated (AmpC enzymes)^[2].

Nka nka

Mpaghara ebumnuche	NDM, KPC, OXA-48, IMP na VIM carbapenemases
Ọnọdụ nchekwa	4 ℃-30 ℃
Ụdị ihe atụ	Ihe atụ nke nje bacteria nwetara mgbe omenala
Ndụ nchekwa	Ọnwa iri abụọ na anọ
Ngwa inyeaka	Ọ dịghị mkpa
Ngwa ahịa ndị ọzọ	Ọ dịghị mkpa
Oge nchọpụta	Ihe atụ nke nje bacteria nwetara mgbe omenala
LoD	Ụdị NDM:0.15ng/mL Ụdị KPC: 0.4ng/mL Ụdị OXA-48:0.1ng/mL Ụdị IMP:0.2ng/mL Ụdị VIM:0.3ng/mL.
Mmetụta nko	Maka NDM, KPC, OXA-48 ụdị carbapenemase, ọ dịghị mmetụta nko dị na nso nke 100ng / mL;maka IMP, ụdị VIM carbapenemase, enweghị mmetụta nko a na-ahụ na nso nke 1μg/mL.