Carbapenemase

Nkọwa Dị Mkpirikpi:

A na-eji ngwa a maka nchọpụta njirimara nke NDM, KPC, OXA-48, IMP na VIM carbapenemases nke e mepụtara na ihe nlele nje bacteria enwetara mgbe e mechara ya na vitro.

Zitere anyị ozi-e

Nkọwa Ngwaahịa

Akara Ngwaahịa

Aha ngwaahịa

Ngwa Nchọpụta Carbapenemase HWTS-OT085E/F/G/H (Colloidal Gold)

Ọmụmụ ihe gbasara ọrịa na-efe efe

Ọgwụ nje Carbapenem bụ ọgwụ nje β-lactam a na-ahụkarị nke nwere ụdị nje bacteria kachasị ukwuu ma nwee ike ime ka nje bacteria sie ike.^[1]N'ihi nkwụsi ike ya na β-lactamase na obere nsí, ọ ghọọla otu n'ime ọgwụ nje kachasị mkpa maka ọgwụgwọ nke ọrịa nje bacteria dị njọ. Carbapenems na-adịgide nke ukwuu maka β-lactamases β-lactamases (ESBLs), kromosomes na cephalosporinases plasmid (enzymes AmpC)^[2].

Usoro Nkà na ụzụ

Mpaghara ebumnuche	NDM, KPC, OXA-48, IMP na VIM carbapenemases
Okpomọkụ nchekwa	4℃-30℃
Ụdị ihe atụ	Ihe nlele nje bacteria enwetara mgbe e mechara omenala
Ndụ nchekwa	Ọnwa iri abụọ na anọ
Ngwa enyemaka	Achọghị ya
Ihe Ndị Ọzọ	Achọghị ya
Oge nchọpụta	Ihe nlele nje bacteria enwetara mgbe e mechara omenala
LoD	Ụdị NDM:0.15ng/mL Ụdị KPC: 0.4ng/mL Ụdị OXA-48:0.1ng/mL Ụdị IMP:0.2ng/mL Ụdị VIM:0.3ng/mL.
Mmetụta nko	Maka NDM, KPC, OXA-48 ụdị carbapenemase, enweghị mmetụta nko dị n'etiti 100ng/mL; maka IMP, ụdị VIM ụdị carbapenemase, enweghị mmetụta nko dị n'etiti 1μg/mL.