Cytomegalovirus mmadụ (HCMV) Nucleic acid

cytomegalovirus mmadụ (HCMV) bụ onye nwere genome kachasị na ezinụlọ nje virus ma nwee ike itinye ihe karịrị protein 200.HCMV ka amachibidoro ya n'ebe ndị mmadụ nọ, ma a ka nwebeghị ụdị anụmanụ nke ọrịa ya.HCMV nwere usoro mmegharị ngwa ngwa na ogologo ogologo iji mepụta ahụ ntinye intranuclear, ma kpalite mmepụta nke perinuclear na cytoplasmic nsonye ahụ na ọzịza cell (nnukwu mkpụrụ ndụ), ya mere aha ya.Dị ka heterogeneity nke genome na phenotype, HCMV nwere ike kewaa n'ime ụdị dị iche iche, n'etiti nke e nwere ụfọdụ antigenic dị iche iche, nke, Otú ọ dị, ọ dịghị mkpa ụlọ ọgwụ.

Ọrịa HCMV bụ ọrịa na-efe efe nke usoro ahụ, nke na-agụnye ọtụtụ akụkụ ahụ, nwere mgbagwoju anya na mgbaàmà dịgasị iche iche, na-emekarị ka ọ dị jụụ, ma nwee ike ime ka ndị ọrịa ole na ole nwee ọnya anụ ahụ gụnyere retinitis, ịba ọcha n'anya, oyi baa, encephalitis, colitis, monocytosis, na thrombocytopenic. purpura.Ọrịa HCMV bụ ihe a na-ahụkarị ma yie ka ọ na-agbasa n'ụwa niile.Ọ na-ewu ewu nke ukwuu na ndị bi na ya, yana ọnụ ọgụgụ omume nke 45-50% na karịa 90% na mba ndị mepere emepe na ndị na-emepe emepe, n'otu n'otu.HCMV nwere ike na-ehi ụra n'ime ahụ ruo ogologo oge.Ozugbo mgbochi ahụ na-ebelata, nje a ga-arụ ọrụ ka ọ bute ọrịa, ọkachasị ọrịa ọrịa leukemia na-ebute ugboro ugboro na ndị ọrịa a na-atụgharị ya, ma nwee ike ibute necrosis akụkụ ahụ a gbanyere n'ahụ ma tinye ndụ ndị ọrịa n'ọnọdụ siri ike.Na mgbakwunye na ịmụ nwa, ime ọpụpụ na nnyefe akaghi aka site na ọrịa intrauterine, cytomegalovirus nwekwara ike ịkpata mmebi nke ọmụmụ, ya mere ọrịa HCMV nwere ike imetụta nlekọta nwa na nlekọta ọmụmụ na ogo mmadụ.