Ntụkọta ROS1 mmadụ

Ros1 bụ nje na-eme njem nke ndị na-eme ka ezinụlọ na-eme ihe. Ekwenyere na Ros1 Fusion Gene dị ka onye ọzọ na-abụghị obere mkpụrụ ndụ cancer cancer counter cance. Dị ka onye nnọchi anya na ịnya ụgbọ mmiri ọhụrụ pụrụ iche, ọnọdụ nke Ros1 Frusion Gene na NSCLC ihe dị ka 1% na 36. Mgbe ejiri ihe nketa mkpụrụ ndụ mmadụ mee ihe dịka CD74, Ee, SLC34A2, na SDC4, ọ ga-aga n'ihu mee ka mpaghara RoS1 mee ka mpaghara Kin1 tinase Kin1. A na-arụ ọrụ Ros1 Kinase nwere ike ịgbalite ụzọ mgbada dị ka Ras / Maapụ, PI3K / PI3K / NATUMS nke Cels, ma na-akpata ọrịa kansa. Otu ihe ndekọ 424, akụkọ CD74, akaụntụ nke CD74, akaụntụ. Studies egosila na saịtị ATP-Inbing nke Ngalaba Ros1 Kinase na saịtị ATP Kintase Kintase na-enwe obere monase na-enwe mmetụta Na ọgwụgwọ nke nsclc na fusiness ọgwụ nke ros1. Ya mere, nchọpụta nke mmụba nke Ros1 bụ ihe eji eme ya ma bụrụ maka iji iwu crizotinib.