Mycobacterium ụkwara nta Nucleic Acid na Rifampicin Nguzogide

Mycobacterium ụkwara nta, obere oge dị ka Tubercle bacillus, TB, bụ nje nje na-akpata ụkwara nta. Ka ọ dị ugbu a, ọgwụ ndị a na-ejikarị alụso ọrịa ọgụ nke mbụ n'ahịrị gụnyere isoniazid, rifampicin na hexambutol, wdg. Ọgwụ mgbochi ụkwara nta nke abụọ gụnyere fluoroquinolones, amikacin na kanamycin, wdg. Ọgwụ ọhụrụ emepụtara bụ linezolid, bedaquiline na delamani, wdg. Otú ọ dị, n'ihi na ezighị ezi ojiji nke ọgwụ mgbochi cell na Ọdịdị nke mgbochi tuberculosis. ụkwara nta, mycobacterium ụkwara nta na-etolite ọgwụ na-eguzogide ọgwụ mgbochi ụkwara nta, nke na-eweta nnukwu ihe ịma aka na mgbochi na ọgwụgwọ ụkwara nta.

A na-eji Rifampicin na-agwọ ndị ọrịa ụkwara nta nke akpa ume kemgbe afọ 1970, ma nwee mmetụta dị ukwuu. Ọ bụ nhọrọ mbụ iji belata ọgwụgwọ ọgwụgwọ nke ndị ọrịa ụkwara nta. Ihe na-akpata nguzogide Rifampicin bụ ngbanwe nke mkpụrụ ndụ ihe nketa rpoB. Ọ bụ ezie na ọgwụ ọhụrụ na-egbochi ụkwara nta na-apụta mgbe nile, na ọgwụgwọ ụlọ ọgwụ nke ndị ọrịa ụkwara nta na-aga n'ihu na-agakwa n'ihu, a ka nwere ụkọ ọgwụ mgbochi ụkwara nta, na ihe na-eme n'iji ọgwụ na-enweghị isi eme ihe na ụlọ ọgwụ dị elu. N'ụzọ doro anya, ọrịa ụkwara nta nke Mycobacterium na-arịa ndị ọrịa nwere ụkwara nta akpa ume enweghị ike igbu ya kpam kpam n'oge, nke na-emecha na-eduga n'ọkwa dị iche iche nke nguzogide ọgwụ n'ahụ onye ọrịa, na-agbatị usoro nke ọrịa ahụ, na-abawanye ohere nke ịnwụ onye ọrịa.