Ọrịa ụkwara nta nke Mycobacterium Nguzogide Nucleic Acid na Rifampicin

Ọrịa ụkwara nta nke Mycobacterium, obere oge ka ọ bụ Tubercle bacillus, TB, bụ nje bacteria na-akpata ụkwara nta. Ugbu a, ọgwụ mgbochi ụkwara nta nke mbụ a na-ejikarị eme ihe gụnyere isoniazid, rifampicin na hexambutol, wdg. Ọgwụ mgbochi ụkwara nta nke abụọ gụnyere fluoroquinolones, amikacin na kanamycin, wdg. Ọgwụ ọhụrụ ndị a mepụtara bụ linezolid, bedaquiline na delamani, wdg. Agbanyeghị, n'ihi ojiji na-ezighi ezi nke ọgwụ mgbochi ụkwara nta na njirimara nke usoro mgbidi sel nke ụkwara nta mycobacterium, ụkwara nta mycobacterium na-emepụta iguzogide ọgwụ mgbochi ụkwara nta, nke na-eweta nnukwu ihe ịma aka na mgbochi na ọgwụgwọ ụkwara nta.

Kemgbe ngwụcha afọ 1970, a na-eji Rifampicin agwọ ndị ọrịa ụkwara nta akpa ume nke ukwuu, ọ na-enwekwa mmetụta dị ukwuu. Ọ bụ nhọrọ mbụ iji belata ọgwụ chemotherapy nke ndị ọrịa ụkwara nta akpa ume. Ihe kpatara ya bụ mgbanwe nke mkpụrụ ndụ ihe nketa rpoB. Ọ bụ ezie na ọgwụ mgbochi ụkwara nta ọhụrụ na-apụta mgbe niile, na arụmọrụ ọgwụgwọ nke ndị ọrịa ụkwara nta akpa ume anọgidewokwa na-aka mma, enwere obere ọgwụ mgbochi ụkwara nta, ihe omume nke iji ọgwụ na-enweghị isi na ọgwụgwọ dị elu. N'ụzọ doro anya, ụkwara nta Mycobacterium na ndị ọrịa nwere ụkwara nta akpa ume enweghị ike igbu kpamkpam n'oge, nke na-emesịa na-ebute oke dị iche iche nke iguzogide ọgwụ n'ahụ onye ọrịa, na-agbatị oge ọrịa ahụ, ma na-eme ka ohere nke ọnwụ nke onye ọrịa dịkwuo elu.