Nchọpụta BCR-ABLET maka ọgwụgwọ cmL

Mywagenoounuemia (cml) bụ ọrịa na-adịghị mma nke mkpụrụ ndụ nke hematopootiiki. Ihe karịrị 95% nke ndị ọrịa CML na-ebu Philadelphia chromosome (pH) na mkpụrụ ndụ ọbara ha. Na bcr-abl-Abl-Abl-awara awara site na nsụgharị n'etiti Abl Contogene (9Q34) na mpaghara Creative (BCR) Gene na ogwe aka nke chromosome 22 (22Q11). Ihe eji eme ya na-eme ka ọ bụrụ nke a na-eme ihe nkiri (TK) na-emegharị (dị ka Ras, PI3K, na-eme ka sel na-eme mkpọtụ, na-eme ka sel na-akpata ihe omume nke cml.

Bcr-abl gele, nke dị mkpa na mmepe nke cmL, na-arụ ọrụ dị ka akara nchoputa nyocha nke cml. Nchọpụta ya na-enyere aka nyochaa onye ọrịa'Nzaghachi na-ezighị aka na-egbochi ndị na-efe efe (TKIS) ma buru amụma na-elegharị anya, nke dị mkpa iji rụọ ọrụ cmL onye ọrịa ọrịa cmL dị irè.

Mmadu brc-ablFolum Gene Montation KitSite na Macro & Micro-ule maka nchọpụta nke bcr-ala na cml, Nchọpụta CmL na-eduzi nyocha nyocha Iji bulie usoro ọgwụgwọ ọgwụgwọ maka njikwa ọrịa nwere ikee, nkeibukeuruNa mmepe nke cmL,na-eje ozi dị ka akara nchoputaofNje osisi cmL. Nchọpụta ya na-enyere akaileba anyainwe ndidi'sNzaghachi na-egbochi ndị na-efe efe (TKIS)naAmụma nyocha Leukemia, nke bụndikato keoru omaNje osisi cmLNjikwa nlekọta.

Mmadụ bcc-abl ablion ihe ngosi site na Macro & Micro-ule maka nchọpụta nke BCR-ABL na CML ndị ọrịa, na-enyere akaNje osisi cmLnchoputanaiduziỌgwụgwọ nyochatoisizikaeUsoro ọgwụgwọ maka njikwa onye ọrịa.

KeukwuDetcation:Nke imekotaotuugbotutuntunke3Mkpụrụ ndụ ihe nketa a na-ahụkarị (P210, p190, p230)nkemkpuchi naMgbochi si n'ọnọdụ ndị funahụrụ;

Nnukwu mmetụta:Mpempe akwụkwọ mmiri mmiri na-achọpụta mkpụrụ ndụ mkpụrụ ndụya na lodnke 1000 / ml,na ụdị lyophidzedof 500 mbipụta / ml;

Kacha mmaACcuracy: Injegheike nchikotana Eng enzyme iji gbochie ihe ojoo&na-ezighi ezi;

Ọrụ dị mfe na arụmọrụ:Na-eme emechi,nke ngwaahịaNhazi post,natutuntunimeNkeji 60nkeEbumnuche na ebumnuche ndị a pụrụ ịdabere na ya;

ỌzọNhọrọ:Mmiri mmiri na nke a lụrụghị maka nhọrọ ndị ahịa;

Nchịkọta dịgasị iche:Dakọtara na ọtụtụ usoro pcr maka nnweta nyocha nke ụlọ nyocha.