PCT/IL-6 jikọtara

PCT bụ ihe mmalite nke calcitonin, nke bụ glycoprotein nke mejupụtara 116 amino acids.Ọnụ ego molekụla bụ ihe dịka 12.8kd.Ọ nweghị ọrụ hormonal.N'okpuru ọnọdụ physiological, PCT bụ nke a na-emepụta na nzuzo site na cell thyroid C.N'oge ọrịa nje, macrophages na monocytes na imeju, lymphocytes na endocrin sel na ngụgụ na eriri afọ anụ ahụ synthesize na secrete a nnukwu ego nke PCT n'okpuru edinam nke endotoxin, tumor necrosis factor-α na interleukin-6, na-eduga na a ịrịba mmụba. na ọkwa nke PCT serum.
Interleukin-6 bụ cytokine nke usoro ahụ ji alụso ọrịa ọgụ na-egosipụta n'oge mmerụ mbụ na ọrịa.A na-emepụta ya site na fibroblasts, monocytes / macrophages, T lymphocytes, B lymphocytes, sel epithelial, keratinocytes, na mkpụrụ ndụ tumor dị iche iche.IL-6 mejupụtara ụdọ glycoprotein abụọ, otu bụ agbụ α nke nwere ibu molekụla nke 80kd;nke ọzọ bụ β yinye nwere molekụla arọ nke 130kd[5].Ọ bụrụ na ahụ mmadụ na-akpali site na mbufụt, ọkwa IL-6 na-ebili ngwa ngwa, nke na-eme ka mmeghachi omume imeju dị ukwuu na-akwalite mmepụta nke protein ndị dị ka C-reactive protein (CRP) na serum amyloid A (SAA). ).Ya mere, IL-6 bụ akara mbụ na-ebili mgbe mbufụt pụtara.