● Ọrịa ụkwara nta Mycobacterium
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Mycobacterium Tuberculosis Nucleic Acid na Rifampicin (RIF), Nguzogide (INH)
A na-eji ngwa a maka nchọpụta in vitro nke DNA ụkwara nta Mycobacterium na sputum mmadụ, omenala siri ike (LJ Medium) na omenala mmiri mmiri (MGIT Medium), mmiri ịsa ahụ bronchial, na mgbanwe na mpaghara codon amino acid 507-533 (81bp, mpaghara mkpebi mgbochi rifampicin) nke mkpụrụ ndụ ihe nketa rpoB nke iguzogide ụkwara nta Mycobacterium rifampicin, yana mgbanwe na ebe mgbanwe bụ isi nke iguzogide isoniazid nke ụkwara nta Mycobacterium. Ọ na-enyere aka na nchọpụta nke ọrịa ụkwara nta Mycobacterium, ọ na-achọpụtakwa mkpụrụ ndụ ihe nketa mgbochi nke rifampicin na isoniazid, nke na-enyere aka ịghọta iguzogide ọgwụ nke ụkwara nta Mycobacterium nke onye ọrịa butere.
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Mgbanwe nke Mycobacterium Tuberculosis INH
Ngwa a dabara adaba maka nchọpụta nke ebe mgbanwe bụ isi na ihe nlele sputum mmadụ nke anakọtara site na ndị ọrịa nwere Tubercle bacillus nke na-ebute ọrịa ụkwara nta mycobacterium INH: Mpaghara nkwalite InhA -15C>T, -8T>A, -8T>C; Mpaghara nkwalite AhpC -12C>T, -6G>A; mgbanwe homozygous nke KatG 315 codon 315G>A, 315G>C.
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Ọrịa ụkwara nta nke Mycobacterium Nguzogide Rifampicin
Ngwa a dabara adaba maka nchọpụta àgwà nke mgbanwe homozygous na mpaghara codon amino acid 507-533 nke mkpụrụ ndụ ihe nketa rpoB nke na-akpata iguzogide Mycobacterium tuberculosis rifampicin.
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Ọrịa ụkwara nta nke Mycobacterium Nguzogide Nucleic Acid na Rifampicin
Ngwa a dabara adaba maka nchọpụta nke DNA ụkwara nta Mycobacterium na ihe nlele sputum mmadụ na vitro, yana mgbanwe homozygous na mpaghara codon amino acid 507-533 nke mkpụrụ ndụ ihe nketa rpoB nke na-akpata iguzogide ụkwara nta Mycobacterium rifampicin.
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Mkpụrụ ndụ nje bacteria Mycobacterium DNA
Ọ dị mma maka nchọpụta nke DNA ụkwara nta Mycobacterium n'ime ihe nlele sputum nke mmadụ, ọ dịkwa mma maka nchọpụta enyemaka nke ọrịa ụkwara nta Mycobacterium.
