Ngwa a dabara adaba maka nchọpụta qualitative nke isi ngbanwe saịtị na sputum sample mmadụ anakọtara site na Tubercle bacillus nti ndị ọrịa na-eduga mycobacterium ụkwara nta isoniazid resistance: InhA promoter region -15C>T, -8T>A, -8T>C;AhpC mpaghara nkwalite -12C>T, -6G>A;Mgbanwe homozygous nke KatG 315 codon 315G>A, 315G>C .